Association between milk consumption and lactose malabsorption in Indonesian children

Zhongguo Dang Dai Er Ke Za Zhi. 2021 Oct 15;23(10):975-980. doi: 10.7499/j.issn.1008-8830.2105030.
[Article in English, Chinese]

Abstract

Objectives: To study the association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years.

Methods: This cross sectional study was conducted in randomly selected presumed healthy children with good nutritional status aged 3-12 years in Central Jakarta, Indonesia (n=174), including 72 children aged 3-5 years and 102 children aged 6-12 years.

Results: The prevalence of lactose malabsorption in children aged 3-5 years and children aged 6-12 years was 20.8% (15/72) and 35.3% (36/102), respectively. There was no association between milk or milk product consumption and lactose malabsorption (P>0.05). In the 51 children with lactose malabsorption, the predominant clinical symptoms were diarrhea (62%), abdominal pain (52%), and nausea (5%) during the hydrogen breath test.

Conclusions: There is no association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years, suggesting that genetic predisposition may be more important than adaptive mechanisms to lactose consumption.

目的: 探讨3~12岁印度尼西亚儿童牛奶摄入与乳糖吸收不良之间的关系。方法: 该研究为横断面研究。研究对象为在印度尼西亚雅加达中部随机选取的营养状况良好的174名3~12岁健康儿童,包括72名3~5岁儿童和102名6~12岁儿童。结果: 3~5岁儿童乳糖吸收不良患病率为20.8%(15/72),6~12岁儿童乳糖吸收不良患病率为35.3%(36/102)。牛奶或乳制品摄入与乳糖吸收不良之间无显著关联性(P>0.05)。在氢呼气试验中,51例乳糖吸收不良儿童主要表现为腹泻(62%)、腹痛(52%)和恶心(5%)。结论: 3~12岁印度尼西亚儿童牛奶摄入和乳糖吸收不良无关联,这提示遗传易感性可能比乳糖摄入的适应机制更重要。.

目的: 探讨3~12岁印度尼西亚儿童牛奶摄入与乳糖吸收不良之间的关系。

方法: 该研究为横断面研究。研究对象为在印度尼西亚雅加达中部随机选取的营养状况良好的174名3~12岁健康儿童,包括72名3~5岁儿童和102名6~12岁儿童。

结果: 3~5岁儿童乳糖吸收不良患病率为20.8%(15/72),6~12岁儿童乳糖吸收不良患病率为35.3%(36/102)。牛奶或乳制品摄入与乳糖吸收不良之间无显著关联性(P>0.05)。在氢呼气试验中,51例乳糖吸收不良儿童主要表现为腹泻(62%)、腹痛(52%)和恶心(5%)。

结论: 3~12岁印度尼西亚儿童牛奶摄入和乳糖吸收不良无关联,这提示遗传易感性可能比乳糖摄入的适应机制更重要。

Keywords: Child; Hydrogen breath test; Lactose malabsorption; Milk consumption; Prevalence.

MeSH terms

  • Animals
  • Breath Tests
  • Child
  • Cross-Sectional Studies
  • Humans
  • Indonesia / epidemiology
  • Lactose Intolerance* / epidemiology
  • Milk