Phacoemulsification combined with micropulse cyclodiode laser in glaucoma patients: efficacy and safety

Eye (Lond). 2022 Nov;36(11):2188-2191. doi: 10.1038/s41433-021-01826-1. Epub 2021 Nov 6.

Abstract

Objective: To evaluate the safety and efficacy of phacoemulsification combined with Micropulse transscleral cyclophotocoagulation (MP-TSCPC) in glaucoma patients.

Methods: This is a retrospective case-note review. The participants were adult patients with diagnoses of glaucoma and cataract who required a further reduction in IOP or a reduction in the number of glaucoma drops. All consecutive patients who underwent cataract surgery (CS) combined with MP-TSCPC laser between October 2018 and July 2019 were included in the study. The effect on visual acuity (VA), intraocular pressure (IOP) and number of anti-glaucoma drops were evaluated at 6 and 12 months in addition to any complications that occurred during any time point of the study.

Results: 42 eyes were included in the study. Mean IOP was reduced from 19.5 ± 5.4 mmHg by 22.5% to 15.1 ± 4.6 at 6 months post-operatively and by 19.5% to 15 ± 6.6 mm Hg at 12 months (p < 0.001 at both time points). The number of anti-glaucoma medications also reduced significantly from 2.8 ± 1.3 to 1.6 ± 1.2 at 6 months and to 2.2 ± 1.3 at 12 months (p < 0.001 at both time points). The success rate was 56% at 6 months and 54% at 12 months. 54.7% of our patients who completed 12 months follow up had an improvement or unchanged vision at the last visits.

Conclusion: This is the first study evaluating the effect of cataract surgery combined with MP-TSCPC in glaucoma patients. We demonstrated that this led to a reduction in IOP and the number of anti-glaucoma medications at 6 and 12-month postoperatively. The majority of patients had either stable or better vision at 12 months follow-up.

MeSH terms

  • Adult
  • Cataract* / complications
  • Ciliary Body / surgery
  • Glaucoma* / complications
  • Glaucoma* / surgery
  • Humans
  • Intraocular Pressure
  • Laser Coagulation
  • Lasers, Semiconductor / therapeutic use
  • Phacoemulsification*
  • Retrospective Studies
  • Treatment Outcome