Disruptive mood dysregulation disorder (DMDD) is a condition in which children or adolescents experience chronically irritable or angry mood. These feelings typically manifest through frequent and intense temper outbursts that can be verbal (eg, yelling) or physical (eg, hitting). These symptoms carry a personal cost, affecting family life, peer relationships, and school functioning. Yet, evidence-based treatment options can be difficult to access. A recent therapeutic solution-Cognitive Bias Modification (CBM)-lies in targeting neurocognitive mechanisms known to maintain and contribute to irritability. In this issue, Haller and colleagues use a fast-fail approach (based on a pre-registered study protocol) to evaluate the potential of a new CBM intervention for young people with DMDD. Here, we discuss what work is needed before the potential of this intervention can be translated for clinical use..
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