Predisposing factors for person-to-person transmission of severe fever with thrombocytopenia syndrome bunyavirus

J Hosp Infect. 2022 May:123:174-178. doi: 10.1016/j.jhin.2021.10.023. Epub 2021 Nov 9.

Abstract

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus (SFTSV) is a new threat to human health. Here we report an outbreak of nosocomial person-to-person transmission of SFTS. Among eight persons with face-to-face contact distance ≤50 cm and/or exposure time ≥30 min to the index patient, six became infected. Only one of the 17 persons with exposure distance ≥50 cm and exposure time ≤30 min became infected (75% vs 6.25%, P < 0.001). Epidemiological investigation revealed high viral load, bloody secretions and bleeding, exposure time, and distance as the key factors in person-to-person transmission.

Keywords: Aerosol transmission; Face shield; Medical protective mask; Person-to-person; Protective measures; Severe fever with thrombocytopenia syndrome.

MeSH terms

  • Causality
  • China / epidemiology
  • Disease Outbreaks
  • Humans
  • Phlebovirus*