Non-homologous chromosome pairing: sequence similarity or genetic control?

Trends Genet. 2022 May;38(5):419-421. doi: 10.1016/j.tig.2021.10.009. Epub 2021 Nov 12.

Abstract

Polyploids must correctly segregate homologous chromosomes. We propose that this process is dictated not just by sequence similarity, but is also under strong genetic control that may vary between lineages. We also highlight how factors like partner availability and genome structure may influence sequence similarity needed for crossover formation.

Keywords: crossovers; homoeologous; meiosis; polyploidy; sequence diversity.

MeSH terms

  • Chromosome Pairing* / genetics
  • Chromosomes / genetics
  • Humans
  • Meiosis*
  • Polyploidy