Crushed bictegravir/emtricitabine/tenofovir alafenamide in a human immunodeficiency virus-positive patient with pancreatic cancer

Int J STD AIDS. 2022 Jan;33(1):97-98. doi: 10.1177/09564624211048702. Epub 2021 Nov 17.

Abstract

We present the case of a 78-year-old African American man with a history of human immunodeficiency virus diagnosed in 2007 who was newly diagnosed with pancreatic cancer. A percutaneous endoscopic gastrostomy tube was placed during the initial inpatient visit of pancreatic cancer diagnosis due to persistent dysphagia. Due to PEG placement and the patient's wish to continue his previous antiretroviral therapy, the patient crushed his fixed-dose bictegravir/emtricitabine/tenofovir alafenamide under the direction of a physician and has maintained virologic suppression.

Keywords: Human immunodeficiency virus; North America; antiretroviral therapy; treatment.

Publication types

  • Case Reports

MeSH terms

  • Adenine / therapeutic use
  • Aged
  • Alanine
  • Amides
  • Anti-HIV Agents* / therapeutic use
  • Emtricitabine / therapeutic use
  • HIV
  • HIV Infections* / complications
  • HIV Infections* / diagnosis
  • HIV Infections* / drug therapy
  • Heterocyclic Compounds, 3-Ring
  • Humans
  • Male
  • Oxazines / therapeutic use
  • Pancreatic Neoplasms* / complications
  • Pancreatic Neoplasms* / drug therapy
  • Piperazines
  • Pyridones
  • Tenofovir / analogs & derivatives
  • Treatment Outcome

Substances

  • Amides
  • Anti-HIV Agents
  • Heterocyclic Compounds, 3-Ring
  • Oxazines
  • Piperazines
  • Pyridones
  • bictegravir
  • Tenofovir
  • tenofovir alafenamide
  • Emtricitabine
  • Adenine
  • Alanine