Hepatic manifestations of systemic disease: an imaging-based review

Pediatr Radiol. 2022 May;52(5):852-864. doi: 10.1007/s00247-021-05222-5. Epub 2021 Nov 19.

Abstract

The liver is responsible for many processes that maintain human metabolic homeostasis and can be affected by several pediatric systemic diseases. In this manuscript, we explore key pathological findings and imaging features across multiple modalities of a spectrum of congenital, metabolic and autoimmune disorders. Strengthening the radiologists' knowledge regarding potential hepatic manifestations of these systemic diseases will ultimately lead to improved care for pediatric patients.

Keywords: Children; Computed tomography; Liver; Magnetic resonance imaging; Systemic disease; Ultrasound.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases*
  • Child
  • Humans
  • Liver / diagnostic imaging
  • Liver / pathology
  • Magnetic Resonance Imaging* / methods
  • Tomography, X-Ray Computed / methods