The neurologic causes of foot and leg dysfunction are reviewed. Disorders causing foot and ankle pain, weakness, or other sensorimotor disturbances often cause difficulty with ambulation and prompt patients to seek medical evaluation. Physical signs and symptoms along with targeted diagnostic testing are needed to come to the correct diagnosis and treatment plan. An overview of peripheral nerve, muscle, and central nervous system disorders affecting the foot and leg are discussed.
Keywords: Ataxia; Cerebral palsy; Charcot–Marie–Tooth disease; Immune-mediated polyneuropathies; Nerve entrapment; Peripheral neuropathy.
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