Choosing Performance-Based Outcome Measures of Daily Living Skills and Socialization for Clinical Trials in Autistic Children

Am J Occup Ther. 2021 Nov 1;75(6):7506205060. doi: 10.5014/ajot.2021.044602.

Abstract

Importance: Robust and psychometrically sound performance-based outcome measures are needed for clinical trials of occupational therapy interventions for children with autism.

Objective: To demonstrate a systematic approach for choosing psychometrically sound performance-based outcome measures of daily living skills and socialization for use in clinical trials of occupational therapy interventions for children with autism.

Design: Rapid literature review to identify appropriate measures for studies with this population followed by quality indicator ratings and a nominal group process.

Setting: University.

Participants: Four experts in autism and pediatric outcome measurement. Outcomes and Measures: Twenty-one outcome measures of daily living skills and socialization were identified and reviewed.

Results: Seven measures met the inclusion criteria. The Assessment of Motor and Process Skills and the Evaluation of Social Interaction-Second Edition, received the highest ratings and group consensus. Several other measures were also scored highly.

Conclusions and relevance: Careful assessment of psychometric properties is an important component of choosing outcome measures for a clinical trial, but burden of assessment and study objectives are important considerations. What This Article Adds: This project demonstrates use of a systematic process for choosing outcome measures for a planned clinical trial.

MeSH terms

  • Autistic Disorder*
  • Child
  • Clinical Trials as Topic
  • Humans
  • Outcome Assessment, Health Care
  • Psychometrics
  • Socialization