Automatic PI-RADS assignment by means of formal methods

Introduction and objectives: The Prostate Imaging Reporting and Data System (PI-RADS) version 2 emerged as standard in prostate magnetic resonance imaging examination. The Pi-RADS scores are assigned by radiologists and indicate the likelihood of a clinically significant cancer. The aim of this paper is to propose a methodology to automatically mark a magnetic resonance imaging with its related PI-RADS.

Materials and methods: We collected a dataset from two different institutions composed by DWI ADC MRI for 91 patients marked by expert radiologists with different PI-RADS score. A formal model is generated starting from a prostate magnetic resonance imaging, and a set of properties related to the different PI-RADS scores are formulated with the help of expert radiologists and pathologists.

Results: Our methodology relies on the adoption of formal methods and radiomic features, and in the experimental analysis, we obtain a specificity and sensitivity equal to 1.

Q conclusions: The proposed methodology is able to assign the PI-RADS score by analyzing prostate magnetic resonance imaging with a very high accuracy.