Bilateral breast necrotizing leukocytoclastic vasculitis: First case report

Breast J. 2021 Dec;27(12):895-898. doi: 10.1111/tbj.14300. Epub 2021 Nov 28.

Abstract

Leukocytoclastic vasculitis (LCV) is a very rare immune complex-mediated condition affecting the small vessels walls. We present the case of a 48-year-old woman with necrotizing bilateral breast LCV on treatment with glatiramer acetate for multiple sclerosis. Bilateral mastectomies and debridement of the anterior abdominal wall were required due to the rapidly evolving necrotizing process. Rapid assessment and a multidisciplinary approach are fundamental in treating this rare life-threatening condition.

Keywords: bilateral mastectomies; leucocytoclastic vasculitis; necrotising fasciitis; necrotising leucocytoclastic vasculitis; necrotising vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Breast / diagnostic imaging
  • Breast / surgery
  • Breast Neoplasms*
  • Fasciitis, Necrotizing*
  • Female
  • Humans
  • Middle Aged
  • Vasculitis, Leukocytoclastic, Cutaneous* / diagnosis
  • Vasculitis, Leukocytoclastic, Cutaneous* / drug therapy

Supplementary concepts

  • Erythema elevatum diutinum