1 From the Université de Paris (MA, FJ-M, SD), Fédération Hospitalo-Universitaire I2-D2, (MA, FJ-M, SD), Department of Anaesthesia and Intensive Care, Robert Debré Hospital, 48 boulevard Sérurier, Paris, France (MA, FJ-M, SD), Department of Anaesthesia & Pain Management, Royal Children's Hospital (CB), Anaesthesia and Pain Management Research Group, Murdoch Children's Research Institute (CB) and Centre for Integrated Critical Care, University of Melbourne, Melbourne, Australia (CB).