New York's Polyethnic-1000: a regional initiative to understand how diverse ancestries influence the risk, progression, and treatment of cancers

Nicolas Robine; Harold Varmus

doi:10.1016/j.trecan.2021.11.005

New York's Polyethnic-1000: a regional initiative to understand how diverse ancestries influence the risk, progression, and treatment of cancers

Trends Cancer. 2022 Apr;8(4):269-272. doi: 10.1016/j.trecan.2021.11.005. Epub 2021 Dec 9.

Authors

Nicolas Robine¹, Harold Varmus²

Affiliations

¹ New York Genome Center, New York, NY, USA. Electronic address: [email protected].
² New York Genome Center, New York, NY, USA; Weill-Cornell Medicine, New York, NY, USA. Electronic address: [email protected].

PMID: 34895873
DOI: 10.1016/j.trecan.2021.11.005

Abstract

Research consortia can help to repair deficiencies in knowledge about the influence of inherited genetic diversity on disease. The New York Genome Center (NYGC) recently established Polyethnic-1000 (P-1000), a multi-institutional collaboration to study hereditary factors affecting several types of cancer. Here, we describe its rationale, organization, development, current activities, and prospects.

Keywords: DNA sequencing; cancer genomes; genetic ancestry; health disparities; research consortia.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Humans
Neoplasms* / genetics
Neoplasms* / therapy
New York