Inhibition of AMPK activity by TRIM11 facilitates cell survival of hepatocellular carcinoma under metabolic stress

Clin Transl Med. 2021 Dec;11(12):e617. doi: 10.1002/ctm2.617.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AMP-Activated Protein Kinase Kinases / antagonists & inhibitors*
  • Carcinoma, Hepatocellular / drug therapy*
  • Carcinoma, Hepatocellular / physiopathology
  • Cell Survival / drug effects
  • Cell Survival / physiology
  • Humans
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / physiopathology
  • Stress, Physiological / drug effects
  • Stress, Physiological / physiology
  • Tripartite Motif Proteins / metabolism
  • Tripartite Motif Proteins / pharmacology*
  • Ubiquitin-Protein Ligases / metabolism
  • Ubiquitin-Protein Ligases / pharmacology*

Substances

  • Tripartite Motif Proteins
  • TRIM11 protein, human
  • Ubiquitin-Protein Ligases
  • AMP-Activated Protein Kinase Kinases