A comprehensive epidemiological study of rosacea in Germany

Eur J Dermatol. 2021 Dec 1;31(6):744-751. doi: 10.1684/ejd.2021.4165.

Abstract

Background: Rosacea is one of the most common skin diseases causing great distress in affected patients. For optimal patient care, epidemiological studies on disease distribution and clinical aspects are essential.

Objectives: The goal of this study was to provide an updated perspective on the current state of rosacea epidemiology in Germany.

Materials & methods: A cohort of 777 rosacea patients was assessed based on a detailed online questionnaire. Information regarding patients' demographics, course and clinical presentation of rosacea, trigger factors, dermatological consultations, treatment adherence and satisfaction as well as quality of life were obtained.

Results: There was a very high self-reported prevalence of primary and secondary rosacea features (flushing: n = 726, 93.4%; papules/pustules: n = 613, 79.0%; telangiectasia: n = 590, 75.9%; sub jective symptoms: n = 691, 88.9%). However, these clinical findings were often underdiagnosed by the treating physicians, while changes in temperature and ultraviolet radiation were potent triggers across all patients (86.3%, 77.7%, respectively). Disease-related quality of life decreased with the number of drugs prescribed as well as with uncontrolled symptom activity, and was reduced in female patients.

Conclusion: This study is the largest German-based assessment exclusively focusing on rosacea patients covering a variety of clinical aspects to optimize patient care.

Keywords: epidemiologic study; epidemiology; rosacea; symptoms; therapeutic outcome; therapy.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Food / adverse effects
  • Germany / epidemiology
  • Health Care Costs
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Male
  • Medication Adherence
  • Middle Aged
  • Patient Satisfaction
  • Prevalence
  • Quality of Life
  • Rosacea / complications
  • Rosacea / drug therapy
  • Rosacea / epidemiology*
  • Rosacea / pathology
  • Smoking / adverse effects
  • Stress, Psychological / complications
  • Temperature
  • Ultraviolet Rays / adverse effects
  • Young Adult