Composite lymphoma represents 1-4% of lymphomas. Only 8 case reports concerned coexisting follicular lymphoma and mantle cell lymphoma. Here, we report the case of an 81 years old man who has been diagnosed with a composite follicular and in situ mantle cell lymphoma. The use of a large panel of immunohistochemical stains associated with the flow cytometry results have allowed us to make this particular diagnosis. We highlight here a common clonal origin of the composite lymphoma's two entities, as described in previous publications.
Keywords: Composite lymphoma; Follicular lymphoma; In situ mantle cell lymphoma; Lymphome composite; Lymphome folliculaire; Lymphome à cellules du manteau; Lymphome à cellules du manteau in situ; Mantle cell lymphoma.
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