Serial case report of high seizure threshold patients that responded to the lengthening of pulse width in ECT

Neuropsychopharmacol Rep. 2022 Mar;42(1):105-108. doi: 10.1002/npr2.12224. Epub 2021 Dec 24.

Abstract

Electroconvulsive therapy (ECT) has been used as an effective treatment modality for psychiatric disorders. In patients with high seizure thresholds, augmentation strategies are considered such as changing anesthetic agents, hyperventilation, and premedication with theophylline. We tried to switch to "long (1.5 ms)" brief pulse ECT in all six patients from October 2020. The successful induction of effective seizures with "long" brief pulse stimulation in five of six patients who could not be treated adequately with standard ECT. In the current situation in cases in which brief pulse ECT, with the maximum dose did not lead to effective seizures, "long" brief pulse waves may be a promising option.

Keywords: electroconvulsive therapy; seizure thresholds; thymatron; “long” brief pulse waves.

Publication types

  • Case Reports

MeSH terms

  • Electroconvulsive Therapy*
  • Heart Rate
  • Humans
  • Seizures / etiology
  • Seizures / therapy
  • Treatment Outcome