Carrier Protein-Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC

Hülya Aldemir; Shuangjie Shu; Francoise Schaefers; Hanna Hong; René Richarz; Sabrina Harteis; Manuel Einsiedler; Tobias M Milzarek; Sabine Schneider; Tobias A M Gulder

doi:10.1002/chem.202104451

Carrier Protein-Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC

Chemistry. 2022 Jan 10;28(2):e202104451. doi: 10.1002/chem.202104451. Epub 2021 Dec 27.

Authors

Affiliations

¹ Chair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069, Dresden, Germany.
² Biosystems Chemistry, Faculty of Chemistry, Technical University of Munich, Lichtenbergstraße 4, 85748, Garching, Germany.
³ Department of Chemistry, Ludwig-Maximillians-University Munich, Butenandtstraße 5-13, 81377, Munich, Germany.

PMID: 34958155
DOI: 10.1002/chem.202104451

Abstract

Invited for the cover of this issue are Sabine Schneider, Tobias A. M. Gulder and co-workers at Technical University of Dresden, Technical University of Munich and Ludwig-Maximillians-University Munich. The image depicts the crystal structure of the cytochrome P450 AryC from arylomycin biosynthesis. Read the full text of the article at 10.1002/chem.202103389.

MeSH terms

Carrier Proteins*
Cytochrome P-450 Enzyme System*
Humans
Oligopeptides

Substances

Carrier Proteins
Oligopeptides
arylomycin A2
Cytochrome P-450 Enzyme System