Squamous Cell Papilloma of the Oesophagus: A Human Papilloma Virus Lesion

Cureus. 2021 Nov 25;13(11):e19903. doi: 10.7759/cureus.19903. eCollection 2021 Nov.

Abstract

Oesophageal squamous cell papilloma is a very rare entity with a limited number of reports in the literature. The exact aetiology is uncertain, and it commonly overlaps with gastro-oesophageal reflux. Human papilloma virus (HPV) is deemed responsible for some cases. Although incidental discovery during upper gastrointestinal endoscopy for other reasons is the commonest presentation, symptomatic cases do occur. Endoscopic excision is the standard treatment. We report a case of HPV-positive squamous papilloma of the upper oesophagus, presenting with lateralising throat pain and diagnosed with office transnasal oesophagoscopy. We also discuss features of HPV-positive oesophageal squamous papilloma and the role of transnasal oesophagoscopy as a recent diagnostic modality of increasing popularity.

Keywords: human papillomavirus (hpv); oesophagus; reflux; squamous papilloma; transnasal oesophagoscopy.

Publication types

  • Case Reports