Marrow ring sideroblasts are highly predictive for TP53 mutation in MDS with excess blasts
Leukemia
.
2022 Apr;36(4):1189-1192.
doi: 10.1038/s41375-021-01486-w.
Epub 2022 Jan 3.
Authors
David M Swoboda
1
2
,
Rashmi Kanagal-Shamanna
3
,
Andrew M Brunner
4
,
Thomas Cluzeau
5
,
Onyee Chan
1
,
Najla Al Ali
1
,
Guillermo Montalban-Bravo
6
,
Quinto J Gesiotto
7
,
Alexander Gavralidis
8
,
Anthony M Hunter
9
,
Jung-Hoon Lee
10
,
Andrew T Kuykendall
1
,
Chetasi Talati
1
,
Kendra L Sweet
1
,
Jeffrey E Lancet
1
,
Eric Padron
1
,
Mohammad Hussaini
11
,
Jinming Song
11
,
Guillermo Garcia-Manero
6
,
Rami S Komrokji
1
,
David A Sallman
12
Affiliations
1
Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
2
Tampa General Hospital Cancer Institute, Tampa, FL, USA.
3
Department of Hematopathology and Molecular Diagnostics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
4
Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
5
Department of Hematology, CHU of Nice, Nice, France.
6
Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
7
Department of Medicine, University of South Florida, Tampa, FL, USA.
8
Department of Internal Medicine, Mass General Brigham Salem Hospital, Boston, MA, USA.
9
Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.
10
Department of Hematology and Medical Oncology, Weill Cornell Medical College, New York, NY, USA.
11
Department of Pathology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
12
Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
[email protected]
.
PMID:
34975158
DOI:
10.1038/s41375-021-01486-w
No abstract available
Publication types
Letter
MeSH terms
Anemia, Sideroblastic* / genetics
Bone Marrow*
Humans
Mutation
RNA Splicing Factors / genetics
Tumor Suppressor Protein p53 / genetics
Substances
RNA Splicing Factors
TP53 protein, human
Tumor Suppressor Protein p53