Paeoniflorin inhibits pyroptosis of nucleus pulposus cells in an acidic environment and alleviates the degeneration of the intervertebral disc in rats

Cell Signal. 2022 Mar:91:110243. doi: 10.1016/j.cellsig.2022.110243. Epub 2022 Jan 4.

Authors

Wang-Ying Dai¹, Zong-Ping Luo²

Affiliations

¹ Orthopaedic Institute, Department of Orthopaedics, The First Affiliated Hospital of Soochow University, 708 Renmin Rd, Suzhou, Jiangsu 215007, PR China.
² Orthopaedic Institute, Department of Orthopaedics, The First Affiliated Hospital of Soochow University, 708 Renmin Rd, Suzhou, Jiangsu 215007, PR China. Electronic address: [email protected].

PMID: 34995750
DOI: 10.1016/j.cellsig.2022.110243

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Glucosides / pharmacology
Intervertebral Disc*
Monoterpenes
Nucleus Pulposus*
Pyroptosis
Rats

Substances

Glucosides
Monoterpenes
peoniflorin