Pillar[5]arene-derived covalent organic materials with pre-encoded molecular recognition for targeted and synergistic cancer photo- and chemotherapy

Chem Commun (Camb). 2022 Feb 3;58(11):1689-1692. doi: 10.1039/d1cc07072j.

Abstract

An efficient targeted and synergistic cancer photo- and chemotherapy platform was constructed from aldehyde-modified pillar[5]arene and tetra-(4-aminophenyl)porphyrin successfully.

MeSH terms

  • Aldehydes / chemistry
  • Antineoplastic Agents* / chemistry
  • Antineoplastic Agents* / pharmacology
  • Calixarenes* / chemistry
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Molecular Structure
  • Photochemotherapy
  • Photosensitizing Agents / chemistry
  • Photosensitizing Agents / pharmacology
  • Porphyrins / chemistry
  • Quaternary Ammonium Compounds* / chemistry

Substances

  • pillar(5)arene
  • Calixarenes
  • Quaternary Ammonium Compounds
  • Antineoplastic Agents
  • Porphyrins
  • Photosensitizing Agents
  • Aldehydes