Adult-onset nephrotic syndrome following coronavirus disease vaccination

Vivek Biradar; Abhijit Konnur; Sishir Gang; Umapati Hegde; Mohan Rajapurkar; Hardik Patel; Sachida Nand Pandey; Shailesh Soni

doi:10.1093/ckj/sfab153

Adult-onset nephrotic syndrome following coronavirus disease vaccination

Clin Kidney J. 2021 Aug 28;15(1):168-170. doi: 10.1093/ckj/sfab153. eCollection 2022 Jan.

Authors

Vivek Biradar¹, Abhijit Konnur¹, Sishir Gang¹, Umapati Hegde¹, Mohan Rajapurkar¹, Hardik Patel¹, Sachida Nand Pandey¹, Shailesh Soni¹

Affiliation

¹ Department of Nephrology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India.

Abstract

A 22-year-old healthy man was admitted for oedema 15 days after the first injection of the COVISHIELD coronavirus disease 2019 (COVID-19) vaccine (Oxford AstraZeneca) vaccine. Nephrotic syndrome was diagnosed and a kidney biopsy showed minimal change disease. Oral prednisolone was started at 1 mg/kg/day resulting in complete remission within 1 week.

Keywords: COVID-19 vaccine; COVISHIELD; minimal change disease; nephrotic syndrome; steroids.