Staphylococcus Aureus Infective Endocarditis: JACC Patient Pathways

Julia Grapsa; Christopher Blauth; Y S Chandrashekhar; Bernard Prendergast; Blair Erb Jr; Michael Mack; Valentin Fuster

doi:10.1016/j.jaccas.2021.10.002

Staphylococcus Aureus Infective Endocarditis: JACC Patient Pathways

JACC Case Rep. 2021 Nov 15;4(1):1-12. doi: 10.1016/j.jaccas.2021.10.002. eCollection 2022 Jan 5.

Authors

Julia Grapsa¹, Christopher Blauth¹, Y S Chandrashekhar², Bernard Prendergast¹, Blair Erb Jr³, Michael Mack⁴, Valentin Fuster^{5

6}

Affiliations

¹ Department of Cardiovascular Sciences, Guys and St Thomas NHS Trust, London, United Kingdom.
² University of Minnesota, Minneapolis, Minnesota, USA.
³ Bozeman Health Deaconess Hospital, Bozeman, Montana, USA.
⁴ Department of Cardiac Surgery, Baylor Scott and White Health, Plano, Texas, USA.
⁵ The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
⁶ Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.

Abstract

A 19-year-old female patient presented with Staphylococcus aureus infective endocarditis, with suspected subdural brain hemorrhage, disseminated intravascular coagulopathy, and septic renal as well as spleen infarcts. The patient had extensive vegetations on the mitral and tricuspid valves and underwent urgent mitral and tricuspid repair. This paper discusses the clinical case and current evidence regarding the management and treatment of Staphylococcus aureus endocarditis.

Keywords: ABx, antibiotic; CIED, cardiac implantable electronic device; CT, computed tomography; ECG, electrocardiogram; ECMO, extracorporeal membrane oxygenation; IE, infective endocarditis; MRSA, methicillin-resistant Staphylococcus aureus; PVE, prosthetic valve infective endocarditis; TEE, transesophageal echocardiogram; TTE, transthoracic echocardiogram; bacteremia; complications; infective endocarditis; staphylococcus aureus; surgery.

Publication types

Review