Identification of the novel HLA-DRB1*04:335 allele by next-generation sequencing

HLA. 2022 Jun;99(6):656-657. doi: 10.1111/tan.14551. Epub 2022 Apr 12.

Authors

Chloé Bost¹, Charlène Bouthemy¹, Marine Cargou², Marylise Fort¹, Nicolas Congy-Jolivet¹

Affiliations

¹ CHU Toulouse, Laboratoire d'Immunologie, Institut fédératif de biologie, Hôpital Purpan, Toulouse, France.
² CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Bordeaux, France.

PMID: 35043590
DOI: 10.1111/tan.14551

Abstract

HLA-DRB1*04:335 differs from DRB1*04:01:01 by one nucleotide substitution in codon 28 in exon 2.

Keywords: HLA; HLA-DRB1*04:335; next-generation sequencing; novel allele.

© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Exons / genetics
HLA-DRB1 Chains / genetics
High-Throughput Nucleotide Sequencing*
Humans

Substances

HLA-DRB1 Chains
HLA-DRB1*04 antigen