Acute respiratory distress syndrome (ARDS) after pressurized intraperitoneal aerosol chemotherapy with oxaliplatin: a case report

Pleura Peritoneum. 2021 Oct 5;6(4):167-170. doi: 10.1515/pp-2021-0126. eCollection 2021 Dec.

Abstract

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new drug delivery method for intraabdominal cavity chemotherapy. It combines the benefits of a minimally invasive approach (low morbidity and easy to repeat) with the pharmacokinetic advantages of intraperitoneal administration and tolerance seems excellent. We would like to report one case of a serious adverse event, acute respiratory distress syndrome, which is likely related to oxaliplatin administration; all signs disappeared within a few days.

Keywords: PIPAC; acute respiratory distress syndrome; complications; oxaliplatin; peritoneal carcinomatosis.