Neutrophil to lymphocyte ratio as a predictor for treatment of radiation-induced brain necrosis with bevacizumab in nasopharyngeal carcinoma patients

Clin Transl Med. 2022 Jan;12(1):e583. doi: 10.1002/ctm2.583.

Authors

Jinhua Cai¹, Ruiqi Xue¹, Zongwei Yue¹, Zhan Zhang¹, Lei He¹, Honghong Li¹, Yi Li¹, Xiaoming Rong¹, Xiaoni Zhang¹, Yongteng Xu¹, Yamei Tang^{1

2

3}

Affiliations

¹ Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
² Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
³ Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People's Republic of China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Bevacizumab / pharmacology*
Bevacizumab / therapeutic use
Brain / radiation effects*
Female
Humans
Lymphocytes / classification*
Lymphocytes / physiology
Male
Middle Aged
Nasopharyngeal Neoplasms / complications
Nasopharyngeal Neoplasms / drug therapy
Nasopharyngeal Neoplasms / physiopathology
Necrosis / drug therapy*
Necrosis / etiology
Necrosis / physiopathology
Neutrophils / classification*
Neutrophils / physiology
Predictive Value of Tests
Radiotherapy / adverse effects
Radiotherapy / methods
Radiotherapy / statistics & numerical data

Substances

Bevacizumab

Grants and funding

This work was supported by the National Natural Science Foundation of China (grant numbers: 81925031 and 81820108026), and the Science and Technology Program of Guangzhou (grant number: 202007030001) to Yamei Tang; the National Natural Science Foundation of China (grant number: 81872549) to Yi Li; the National Natural Science Foundation of China (grant number: 82003389) to Honghong Li; the Youth Program of National Natural Science Foundation of China (grant number: 81801229) to Yongteng Xu