Isolation of a Ceftazidime-Avibactam-Resistant bla_KPC-71-Positive Klebsiella pneumoniae Clinical Isolate

Microbiol Spectr. 2022 Feb 23;10(1):e0184021. doi: 10.1128/spectrum.01840-21. Epub 2022 Jan 26.

Authors

Siquan Shen^#^{1

2}, Qingyu Shi^#^{1

2}, Renru Han^{1

2}, Yan Guo^{1

2}, Yang Yang^{1

2}, Shi Wu^{1

2}, Dandan Yin^{1

2}, Fupin Hu^{1

2}

Affiliations

¹ Institute of Antibiotics, Huashan Hospitalgrid.411405.5, Fudan University, Shanghai, China.
² Key Laboratory of Clinical Pharmacology of Antibiotics, Ministry of Health, Shanghai, China.

^# Contributed equally.

No abstract available

Keywords: KPC-2; KPC-71; ST11; ceftazidime/avibactam.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Anti-Bacterial Agents / pharmacology*
Azabicyclo Compounds / pharmacology*
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Ceftazidime / pharmacology*
Drug Combinations
Drug Resistance, Bacterial*
Humans
Klebsiella Infections / microbiology*
Klebsiella pneumoniae / drug effects*
Klebsiella pneumoniae / enzymology
Klebsiella pneumoniae / genetics
Male
Microbial Sensitivity Tests
beta-Lactamases / genetics
beta-Lactamases / metabolism

Substances

Anti-Bacterial Agents
Azabicyclo Compounds
Bacterial Proteins
Drug Combinations
avibactam, ceftazidime drug combination
Ceftazidime
beta-Lactamases