A Rare Cause of Gastric Variceal Bleeding

Yesenia Ramos; Dorina Gui; Eric Chak

doi:10.1159/000521126

A Rare Cause of Gastric Variceal Bleeding

Case Rep Gastroenterol. 2021 Dec 30;15(3):1008-1012. doi: 10.1159/000521126. eCollection 2021 Sep-Dec.

Authors

Yesenia Ramos¹, Dorina Gui², Eric Chak³

Affiliations

¹ Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, California, USA.
² Department of Pathology, University of California Davis School of Medicine, Sacramento, California, USA.
³ Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California, USA.

Abstract

A 68-year-old woman with stage III colon cancer status after right hemicolectomy and adjuvant FOLFOX (5-fluorouracil/leucovorin/oxaliplatin) chemotherapy was hospitalized for melena and found to have new-onset esophageal and gastric varices on esophagogastroduodenoscopy. Her workup did not reveal an underlying liver disease, but her liver biopsy showed noncirrhotic portal hypertension from obliterative portal venopathy (OPV). The development of OPV is likely from her use of oxaliplatin-based chemotherapy.

Keywords: Gastric variceal bleed; Noncirrhotic portal hypertension; Obliterative portal venopathy; Oxaliplatin.

Publication types

Case Reports