Immunomodulatory effects of intestinal lung axis microecology and other factors on the prognosis of advanced non-small cell lung cancer

Changxing Shen; Yanbei Ren; Xu Zhang; Qing Xia; Ming Li; Changhui Wang; Lihong Fan

doi:10.21037/tcr.2019.09.32

Immunomodulatory effects of intestinal lung axis microecology and other factors on the prognosis of advanced non-small cell lung cancer

Transl Cancer Res. 2019 Sep;8(5):2205-2210. doi: 10.21037/tcr.2019.09.32.

Authors

Changxing Shen¹, Yanbei Ren¹, Xu Zhang¹, Qing Xia¹, Ming Li¹, Changhui Wang¹, Lihong Fan¹

Affiliation

¹ Department of Respiratory and Critical Care Medicine, The Tenth People's Hospital affiliated to Tongji University, Shanghai 200072, China.

Abstract

Overall survival (OS) of lung cancer varies greatly with individual patients in the global setting. Multiple factors may affect the prognosis. Different antibiotics have significant effects on the prognosis of lung cancer patients. The intestinal microbiome, nutritional status and inflammatory factors all have significant impact on OS of lung cancer patients.

Keywords: Non-small cell lung cancer (NSCLC); antibiotics; inflammatory immunity; intestinal microecology.

Publication types

Review