Abstract
Seventeen patients with advanced lymphoma were treated with high-dose chemotherapy with autologous bone marrow rescue. In 11 patients with non-Hodgkin's lymphoma (NHL) there were 2 complete remissions (CRs) and 2 partial remissions (PRs), and in 6 patients with Hodgkin's disease there were 5 CRs. Three patients remain well in unmaintained remission (days 874, 446 and 351), and a further 2 are alive and still receiving treatment (days 650 and 558). This type of therapy appears useful and should now be considered earlier in the course of the disease.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Bone Marrow Transplantation*
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Carmustine / therapeutic use
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Cyclophosphamide / therapeutic use
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Cytarabine / therapeutic use
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Female
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Hodgkin Disease / drug therapy*
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Hodgkin Disease / therapy
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Humans
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Lymphoma / drug therapy*
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Lymphoma / therapy
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Male
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Melphalan / therapeutic use
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Methotrexate / therapeutic use
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Middle Aged
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Podophyllotoxin / therapeutic use
Substances
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Cytarabine
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Cyclophosphamide
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Podophyllotoxin
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Melphalan
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Carmustine
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Methotrexate
Supplementary concepts
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BEAM protocol
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UCH I protocol
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UCH II protocol