First reported case of delayed-type hypersensitivity reaction to non-hyaluronic acid Polycaprolactone dermal filler following COVID-19 vaccination: A case report and a review of the literature

Yasamin Kalantari; Afsaneh Sadeghzadeh-Bazargan; Zeinab Aryanian; Parvaneh Hatami; Azadeh Goodarzi

doi:10.1002/ccr3.5343

First reported case of delayed-type hypersensitivity reaction to non-hyaluronic acid Polycaprolactone dermal filler following COVID-19 vaccination: A case report and a review of the literature

Clin Case Rep. 2022 Feb 6;10(2):e05343. doi: 10.1002/ccr3.5343. eCollection 2022 Feb.

Authors

Yasamin Kalantari¹, Afsaneh Sadeghzadeh-Bazargan², Zeinab Aryanian^{3

4}, Parvaneh Hatami³, Azadeh Goodarzi^{2

5}

Affiliations

¹ Department of Dermatology Razi Hospital Tehran University of Medical Sciences Tehran Iran.
² Rasool Akram Medical Complex Clinical Research Development Center (RCRDC) School of Medicine Iran University of Medical Sciences Tehran Iran.
³ Autoimmune Bullous Diseases Research Center Tehran University of Medical Sciences Tehran Iran.
⁴ Department of Dermatology Babol University of Medical Sciences Babol Iran.
⁵ Skin and Stem Cell Research Center Tehran University of Medical Sciences Tehran Iran.

Abstract

Cases of filler reactions after COVID-19 vaccination have been reported. Here, we present the first case of delayed-type reaction (DTR) to non-hyaluronic acid Polycaprolactone dermal filler after the second dose of Sinopharm COVID-19 vaccine which was improved with administration of topical and intralesional steroids.

Keywords: COVID‐19; COVID‐19 vaccines; adverse effects; augmentation; case report; coronavirus; cosmetic; cosmetic filler; delayed‐type reaction; dermal fillers; hyaluronic acid; hyaluronic acid fillers; non‐hyaluronic acid fillers; review; side effects; swelling; vaccination.

Publication types

Case Reports