Antimicrobial Peptides as a Promising Therapeutic Strategy for Neisseria Infections

Curr Microbiol. 2022 Feb 13;79(4):102. doi: 10.1007/s00284-022-02767-y.

Abstract

Antibiotic resistance is already widespread in the world, and it has become a great health problem. Therefore, comprehensive efforts are needed to minimize the resistance. The exploration of alternative therapies may offer a more targeted approach with less susceptibility to resistance. Even though antimicrobial peptides (AMPs) have been introduced as emerging antibiotic sources, they are not widely discussed in the literature. Since Neisseria infections show resistance to different types of antibiotics, the purpose of this review was to discuss the currently investigated AMPs with anti-Neisseria properties. In the present review, we provide an overview of 24 AMPs with in vitro anti-Neisseria properties.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Antimicrobial Cationic Peptides* / pharmacology
  • Antimicrobial Peptides*
  • Drug Resistance, Microbial
  • Neisseria

Substances

  • Anti-Bacterial Agents
  • Antimicrobial Cationic Peptides
  • Antimicrobial Peptides