Germline and Somatic Smoothened Mutations in Non-Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib

Affiliation

• ¹ Anne S. Tsao, Ignacio Wistuba, Dianren Xia, Lauren Byers, Lixia Diao, Jing Wang, Vassiliki Papadimitrakopoulou, Ximing Tang, Wei Lu, Zhi Tan, Shuxing Zhang, Monique Nilsson, and John V. Heymach, The University of Texas MD Anderson Cancer Center, Houston, TX; Humam Kara, American University of Beirut, Beirut, Lebanon; and Dimitry N. Grigoryev, Myvizhi Esai Selvan, and Zeynep H. Gümüş, Icahn School of Medicine at Mount Sinai, New York, NY.