Recent research on the effect of preeclampsia on maternal-infant intestinal flora interactions

Zhongguo Dang Dai Er Ke Za Zhi. 2022 Jan 15;24(1):102-107. doi: 10.7499/j.issn.1008-8830.2110034.
[Article in English, Chinese]

Abstract

Preeclampsia (PE) is a unique complication of pregnancy that affects the health of the mother and the infant. Intestinal flora plays an important regulatory role in human body's metabolism and immunity and is associated with many diseases. Studies have shown that the development and progression of PE can lead to alterations in intestinal flora in the mother and are even closely associated with the colonization and development of intestinal flora in the offspring. This article reviews related studies on the effect of PE on maternal-infant intestinal flora, so as to provide new ideas for the prevention and treatment of maternal and infant complications associated with PE.

子痫前期是妊娠期特有的并发症,影响母婴健康。肠道菌群在人体代谢和免疫方面发挥着重要的调节作用,并与许多疾病相关。研究表明,子痫前期的发生发展可导致母亲肠道菌群的改变,甚至与子代肠道菌群的定植与发展密切相关。该文就子痫前期对母婴肠道菌群影响的相关研究进行综述,为子痫前期相关母婴并发症的预防及治疗提供新思路。.

Keywords: Intestinal flora; Neonate; Preeclampsia; Pregnancy.

Publication types

  • Review

MeSH terms

  • Female
  • Gastrointestinal Microbiome*
  • Humans
  • Infant
  • Pre-Eclampsia* / etiology
  • Pre-Eclampsia* / prevention & control
  • Pregnancy