The anti-FcεRI antibody MAR-1 depletes basophils and cross-reacts with myeloid cells through its Fc portion
Allergy
.
2022 Jun;77(6):1903-1906.
doi: 10.1111/all.15269.
Epub 2022 Mar 11.
Authors
William P M Worrall
1
,
Jasper B J Kamphuis
1
,
Julien Stackowicz
2
3
,
Aurélie Mougel
1
,
Emilie Mauré
1
,
Cyprien Pecalvel
1
,
Sébastien Brûlé
4
,
Pierre Bruhns
2
,
Laurent Guilleminault
1
5
,
Laurent L Reber
1
Affiliations
1
Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), UMR 1291, University of Toulouse, INSERM, CNRS, Toulouse, France.
2
Unit of Antibodies in Therapy and Pathology, Institut Pasteur, Université de Paris, Inserm UMR1222, Paris, France.
3
Sorbonne University, Paris, France.
4
Plateforme de Biophysique Moléculaire, Institut Pasteur, Université de Paris, UMR 3528 CNRS, Paris, France.
5
Department of Respiratory Medicine, University Hospital Centre of Toulouse, Toulouse, France.
PMID:
35244223
DOI:
10.1111/all.15269
No abstract available
Keywords:
IgE; anaphylaxis; basophil; mast cells.
Publication types
Letter
MeSH terms
Basophils*
Cell Degranulation
Humans
Immunoglobulin E
Leukocyte Count
Mast Cells
Receptors, IgE*
Substances
Receptors, IgE
Immunoglobulin E