Esophageal hyperkeratosis as an uncommon manifestation of gastroesophageal reflux disease

Rev Esp Enferm Dig. 2022 Aug;114(8):508. doi: 10.17235/reed.2022.8764/2022.

Abstract

We present the case of a 66-year-old woman with intermittent dysphagia and esophageal food impaction. The endoscopic examination showed an upper and middle esophagus with a diffuse circumferential, white, crackleware epithelium. Esophageal biopsies revealed acanthosis and papillomatosis with diffuse hyperkeratosis. High dose of Proton pump inhibitors was initiated with improvement of all symptoms 6 weeks later.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Biopsy
  • Endoscopy
  • Female
  • Gastroesophageal Reflux* / complications
  • Gastroesophageal Reflux* / diagnosis
  • Gastroesophageal Reflux* / drug therapy
  • Humans
  • Proton Pump Inhibitors / therapeutic use

Substances

  • Proton Pump Inhibitors