In this paper, the problems of decreasing coupling efficiency and energy distribution divergence of water beam fiber caused by static alignment deviation are studied. Based on the basic conditions of coupling between laser and water beam fiber, the mathematical model of coupling efficiency of water beam fiber is established, and the calculation equation of coupling efficiency is modified. The variation of coupling efficiency and energy distribution of water beam fiber under the influence of static alignment deviation is analyzed by numerical simulation, and the correctness of theoretical derivation and simulation model is verified by experiments. The results show that the lateral deviation changes the transmission path of laser in the water beam fiber to a large extent, and its influence on the energy distribution in the water beam fiber is greater than that of longitudinal deviation and angular deviation.