Brain metastasis of non-small cell lung cancer (NSCLC) is a common treatment failure mode, and the median survival time of NSCLC patients with brain metastasis is only 1 mon-2 mon. Prophylactic cranial irradiation (PCI) can delay the occurrence of brain metastasis, but the survival benefits of NSCLC patients are still controversial. It is particularly important to identify the patients who are most likely to benefit from PCI. This article reviews the high risk factors of brain metastasis in NSCLC. .
【中文题目：非小细胞肺癌脑转移高危因素研究进展】 【中文摘要：非小细胞肺癌（non-small cell lung cancer, NSCLC）脑转移是常见的治疗失败模式，发生脑转移的NSCLC患者中位生存时间仅为1个月-2个月。预防性脑照射（prophylactic cranial irradiation, PCI）可延缓脑转移的发生，但对NSCLC患者的生存获益仍存在争议，因此，通过预测脑转移的风险筛选可能从PCI中获益的人群尤为重要。本文就NSCLC脑转移的高危因素进行综述。 】 【中文关键词：肺肿瘤；脑转移；预防性脑照射】.
Keywords: Brain metastasis; Lung neoplasms; Prophylactic cranial irradiation.