Novel Innovation in Flow Diversion: Surface Modifications

Flow diversion is a mainstay of modern endovascular aneurysm treatment. Several surface-modified flow diverters have been introduced with a goal to reduce rates of in-stent thrombosis and the need for dual antiplatelet therapy. Preliminary follow-up data suggest that these now commercially available devices are noninferior with respect to rates of angiographic occlusion. These data also suggest that these devices have lower rates of stent-related ischemia. In this chapter, we explore these devices in detail and discuss clinical data regarding their efficacy. We also discuss an alternative bioactive surface modification strategy that has shown in vitro and in vivo efficacy.