1 Max Jordan Nguemeni Tiako is a resident physician in internal medicine at Brigham and Women's Hospital, Boston, MA. Jules Netherland is the managing director of the Department of Research and Academic Engagement for the Drug Policy Alliance, New York, NY. Helena Hansen is professor and chair of Research Theme in Translational Social Science and Health Equity, as well as associate director of the Center for Social Medicine at David Geffen School of Medicine, University of California, Los Angeles. Marie Jauffret-Roustide is a research fellow at the Institut National de la Santé et de la Recherche Médicale in Paris, France, and affiliate scientist at the British Columbia Centre on Substance Use, Vancouver, Canada. Helena Hansen and Marie Jauffret-Roustide are also Guest Editors of this supplement issue.