Double-blind study of sulindac and aspirin in juvenile chronic arthritis

S Afr Med J. 1986 Dec 6;70(12):724-6.

Abstract

Sulindac (Clinoril; Frosst-MSD), a non-steroidal anti-inflammatory drug was compared with aspirin in a randomized double-blind cross-over controlled study in 30 patients with juvenile chronic arthritis. Sulindac was found to be safe and effective. Although it has the advantage of a twice-a-day dose regimen, both patient and doctor may prefer to be guided by pain relief and cost.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Arthritis, Juvenile / drug therapy*
  • Aspirin / adverse effects
  • Aspirin / therapeutic use*
  • Child
  • Child, Preschool
  • Chronic Disease
  • Clinical Trials as Topic
  • Double-Blind Method
  • Drug Evaluation
  • Female
  • Humans
  • Indenes / therapeutic use*
  • Male
  • Random Allocation
  • Sulindac / adverse effects
  • Sulindac / therapeutic use*

Substances

  • Indenes
  • Sulindac
  • Aspirin