Assessment of glycemia in chronic kidney disease

BMC Med. 2022 Apr 13;20(1):117. doi: 10.1186/s12916-022-02316-1.

Abstract

Reliable assessment of glycemia is central to the management of diabetes. The kidneys play a vital role in maintaining glucose homeostasis through glucose filtration, reabsorption, consumption, and generation. This review article highlights the role of the kidneys in glucose metabolism and discusses the benefits, pitfalls, and evidence behind the glycemic markers in patients with chronic kidney disease. We specifically highlight the role of continuous glucose monitoring as an emerging minimally invasive technique for glycemic assessment.

Keywords: Chronic kidney disease; Continuous glucose monitoring; Diabetes mellitus; Fructosamine; Glycated albumin; Glycemic monitoring; Hemoglobin A1C; One; Self-monitored blood glucose; five-anhydroglucitol; glycemic assessment.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Blood Glucose / metabolism
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 2*
  • Glucose
  • Glycated Hemoglobin / analysis
  • Humans
  • Renal Insufficiency, Chronic* / diagnosis

Substances

  • Biomarkers
  • Blood Glucose
  • Glycated Hemoglobin A
  • Glucose