Mantle cell lymphoma with endobronchial involvement: A case report

Yi-Zong Ding; Dao-Qiang Tang; Xiao-Jing Zhao

doi:10.12998/wjcc.v10.i8.2604

Mantle cell lymphoma with endobronchial involvement: A case report

World J Clin Cases. 2022 Mar 16;10(8):2604-2609. doi: 10.12998/wjcc.v10.i8.2604.

Authors

Yi-Zong Ding¹, Dao-Qiang Tang², Xiao-Jing Zhao³

Affiliations

¹ Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
² Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
³ Department of Thoracic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. [email protected].

Abstract

Background: Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin's lymphoma (NHL). MCL frequently affects extranodal sites while endobronchial involvement is uncommon. Only 5 cases of MCL with endobronchial involvement have been previously reported.

Case summary: A 56-year-old male patient arrived at the hospital complaining of a dry cough. A mass in the right upper lobe of the lung was revealed in Chest computed tomography (CT). Right lung hilar and mediastinal lymphadenopathies were also found by CT scan. The patient was diagnosed with central-type lung cancer with multiple lymph node metastases after positron emission tomography (PET) CT scan examination. The fiber optic bronchoscope examination revealed diffuse neoplasm infiltration in the inlet of the right up lobar bronchus. The patient was finally diagnosed with MCL based on the bronchoscopy and mediastinoscopy biopsy results.

Conclusion: MCL could masquerade as central type lung cancer. An endobronchial biopsy examination is necessary for the early diagnosis of MCL.

Keywords: Bronchoscopy; Case report; Central type lung cancer; Endobronchial biopsy; Endobronchial involvement; Mantle cell lymphoma; Mediastinoscopy.

Publication types

Case Reports