Objective: To explore the quality of life and its influencing factors of enhanced recovery after surgery (ERAS) of esophageal cancer patients. Methods: The quality of life of 134 esophageal cancer patients was assessed using the quality of life assessment scale (EORTC QLQ-C30) developed by the European Cancer Research and Treatment Organization. Student's t test, One-way ANOVA and multiple linear regression statistical methods were used to analyze the effects of sociodemographic and clinical characteristics on patients' quality of life. Results: The overall score of quality of life (74.00) was lower than that of the general population (75.30). However, the scores of emotion and cognition in function dimension (93.97 and 95.77) were better than those of the general population (82.80 and 86.50). The results of fatigue, pain, insomnia and constipation in symptom dimension (14.18, 10.94, 11.69 and 5.72) were better than those of the general population (28.80, 20.50, 20.40 and 10.70). The pathological stage, body mass index and dietary were independent influencing factors for the quality of life of patients with esophageal cancer (P<0.05). Conclusions: ERAS can partially improve the quality of life of esophageal cancer patients. More attention should be paid to the esophageal cancer patients after surgery and take targeted measures to improve their quality of life.
目的： 探讨食管癌患者加速康复术后的生活质量水平及影响因素。 方法： 采用欧洲癌症研究与治疗组织开发的生活质量评估量表对134例食管癌患者的生活质量进行评估。采用t检验、单因素方差分析及多元线性回归等统计方法分析社会人口学、临床特征等因素对患者生活质量的影响。 结果： 食管癌患者总体生活质量得分(74.00分)低于正常人平均得分(常模，75.30分)。功能领域中，情绪和认知功能得分(分别为93.97和95.77分)优于常模(分别为82.80和86.50分)；症状领域中，疲乏、疼痛、失眠和便秘得分(分别为14.18、10.94、11.69和5.72分)优于常模(分别为28.80、20.50、20.40和10.70分)。病理分期、体质指数及进食状况为食管癌患者生活质量的影响因素(均P<0.05)。 结论： 加速康复模式可提高食管癌患者部分生活质量水平。应对食管癌术后患者给予更多关注，采取有针对性的措施提高食管癌患者的生活质量。.
Keywords: Enhanced recovery after surgery; Esophageal neoplasms; Influencing factor; Quality of life.