Risk of Appendicitis After mRNA COVID-19 Vaccination in a Danish Population

Helene Kildegaard; Louise Ladebo; Jacob Harbo Andersen; Peter Bjødstrup Jensen; Lotte Rasmussen; Per Damkier; Anton Pottegård

doi:10.1001/jamainternmed.2022.1222

Risk of Appendicitis After mRNA COVID-19 Vaccination in a Danish Population

JAMA Intern Med. 2022 Jun 1;182(6):684-686. doi: 10.1001/jamainternmed.2022.1222.

Authors

Helene Kildegaard¹, Louise Ladebo¹, Jacob Harbo Andersen¹, Peter Bjødstrup Jensen¹, Lotte Rasmussen¹, Per Damkier^{1

2

3}, Anton Pottegård^{1

4}

Affiliations

¹ Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Odense.
² Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.
³ Department of Clinical Research, University of Southern Denmark, Odense.
⁴ Hospital Pharmacy Funen, Odense University Hospital, Odense, Denmark.

Abstract

This cohort study used data from Danish registers to assess whether recipients of mRNA COVID-19 vaccines had a higher risk of appendicitis after receiving the shot compared with individuals who did not receive the vaccine.

MeSH terms

Appendicitis* / epidemiology
COVID-19 Vaccines* / adverse effects
COVID-19* / prevention & control
Denmark / epidemiology
Humans
Vaccination / adverse effects
mRNA Vaccines* / adverse effects

Substances

COVID-19 Vaccines
mRNA Vaccines