Commentary: Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4+ T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation

Jessica Stokes; Richard J Simpson; Emmanuel Katsanis

doi:10.3389/fimmu.2022.887648

Commentary: Post-Transplantation Cyclophosphamide Uniquely Restrains Alloreactive CD4+ T-Cell Proliferation and Differentiation After Murine MHC-Haploidentical Hematopoietic Cell Transplantation

Front Immunol. 2022 Apr 14:13:887648. doi: 10.3389/fimmu.2022.887648. eCollection 2022.

Authors

Jessica Stokes¹, Richard J Simpson^{1

2

3

4}, Emmanuel Katsanis^{1

2

3

5

6}

Affiliations

¹ Department of Pediatrics, University of Arizona, Tucson, AZ, United States.
² Department of Immunobiology, University of Arizona, Tucson, AZ, United States.
³ The University of Arizona Cancer Center, Tucson, AZ, United States.
⁴ School of Nutritional Sciences and Wellness, University of Arizona, Tucson, AZ, United States.
⁵ Department of Medicine, University of Arizona, Tucson, AZ, United States.
⁶ Department of Pathology, University of Arizona, Tucson, AZ, United States.

No abstract available

Keywords: chemotherapy; graft (regulation); graft versus host disease (GVHD); haploidentical hematopoietic stem cell transplantation; murine (mouse).

Publication types

Comment

MeSH terms

Animals
CD4-Positive T-Lymphocytes*
Cell Differentiation
Cell Proliferation
Cyclophosphamide / pharmacology
Cyclophosphamide / therapeutic use
Hematopoietic Stem Cell Transplantation*
Mice

Substances

Cyclophosphamide