Cardiopulmonary Resuscitation (CPR) is a critical procedure with potential consequences over futu re vitality and functionality in survivors. In this document, we present a pragmatic and regional point of view on diagnosis, management, and prognostication in pediatric CPR developed by the Com mittee on CPR of the Latin American Society of Pediatric Intensive Care (SLACIP). We have chosen the main CPR topics with the aim of contribute for a better prevention and management of CPR, standardize the management of the post-cardiac arrest syndrome and neuro-prognostication, and identify opportunities for regional research. We have followed the Executive Summary published in 2020 by the International Liaison Committee on Resuscitation, ILCOR, adapted it to our reality, and developed this narrative review of pediatric CPR with the contribution of Latin American experts.