[Endometrioid carcinoma of uterus and small-cell neuroendocrine carcinoma of both ovary: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2022 May 8;51(5):467-469. doi: 10.3760/cma.j.cn112151-20210807-00555.
[Article in Chinese]

Abstract

患者女，36岁。乳腺癌术后6年，肝脏血管平滑肌脂肪瘤术后5年，发现盆腔占位。行全子宫双附件及盆腔病灶等切除术，病理证实为子宫体高分化内膜样癌伴双侧卵巢小细胞神经内分泌癌，并子宫肌壁间、浆膜外、大网膜、乙状结肠系膜和右下腹膜转移。免疫组织化学显示：子宫内膜样癌突触素阴性；卵巢小细胞癌上皮标志物、突触素、嗜铬粒素A均阳性，INI1、BRG1无缺失，p53突变型模式，乳腺癌标志物均阴性，微卫星稳定，BRCA1/2无突变。外周血基因检测发现患者TP53基因胚系突变。.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Endometrioid* / pathology
  • Carcinoma, Neuroendocrine* / pathology
  • Carcinoma, Neuroendocrine* / surgery
  • Carcinoma, Small Cell* / surgery
  • Endometrial Neoplasms* / pathology
  • Female
  • Humans
  • Ovarian Neoplasms* / pathology
  • Ovarian Neoplasms* / surgery
  • Uterus / pathology