Health literacy and long-term health outcomes following myocardial infarction: protocol for a multicentre, prospective cohort study (ENHEARTEN study)

Alison Beauchamp; Jason Talevski; Stephen J Nicholls; Anna Wong Shee; Catherine Martin; William Van Gaal; Ernesto Oqueli; Jaithri Ananthapavan; Laveena Sharma; Adrienne O'Neil; Sharon Lee Brennan-Olsen; Rebecca Leigh Jessup

doi:10.1136/bmjopen-2021-060480

Health literacy and long-term health outcomes following myocardial infarction: protocol for a multicentre, prospective cohort study (ENHEARTEN study)

BMJ Open. 2022 May 6;12(5):e060480. doi: 10.1136/bmjopen-2021-060480.

Authors

Alison Beauchamp^{1

2}, Jason Talevski^{3

2

4}, Stephen J Nicholls⁵, Anna Wong Shee^{6

7}, Catherine Martin^{8

9}, William Van Gaal^{10

11}, Ernesto Oqueli^{12

13}, Jaithri Ananthapavan¹⁴, Laveena Sharma^{3

15}, Adrienne O'Neil¹⁶, Sharon Lee Brennan-Olsen¹⁷, Rebecca Leigh Jessup^{18

19}

Affiliations

¹ School of Rural Health, Monash University, Warragul, Victoria, Australia [email protected].
² Department of Medicine - Western Health, The University of Melbourne, Melbourne, Victoria, Australia.
³ School of Rural Health, Monash University, Warragul, Victoria, Australia.
⁴ Institute for Physical Activity and Nutrition Research (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia.
⁵ Monash Cardiovascular Research Centre, Victorian Heart Institute, Monash University, Clayton, Victoria, Australia.
⁶ Allied Health, Ballarat Health Services - Grampians Health, Ballarat, Victoria, Australia.
⁷ Deakin Rural Health, Deakin University, Ballarat, Victoria, Australia.
⁸ Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
⁹ Data Science and AI, Monash University, Melbourne, Victoria, Australia.
¹⁰ Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.
¹¹ Department of Cardiology, The Northern Hospital, Melbourne, Victoria, Australia.
¹² School of Medicine, Deakin University, Burwood, Victoria, Australia.
¹³ Cardiology, Ballarat Health Services - Grampians Health, Ballarat, Vic, Australia.
¹⁴ Deakin Health Economics, School of Health and Social Development, Institute for Health Transformation, Deakin University, Geelong, Victoria, Australia.
¹⁵ Monash Heart, Monash Health, Clayton, Victoria, Australia.
¹⁶ Institute for Mental and Physical Health and Clinical Training, Food & Mood Centre, Deakin University, Geelong, Victoria, 3220.
¹⁷ School of Health and Social Development, Deakin University - Geelong Waterfront Campus, Geelong, Victoria, Australia.
¹⁸ School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Victoria, Australia.
¹⁹ Staying Well Programs, Northern Health, Melbourne, Victoria, Australia.

Abstract

Introduction: Low health literacy is common in people with cardiovascular disease and may be one factor that affects an individual's ability to maintain secondary prevention health behaviours following myocardial infarction (MI). However, little is known about the association between health literacy and longer-term health outcomes in people with MI. The ENhancing HEAlth literacy in secondary pRevenTion of cardiac evENts (ENHEARTEN) study aims to examine the relationship between health literacy and a number of health outcomes (including healthcare costs) in a cohort of patients following their first MI. Findings may provide evidence for the significance of health literacy as a predictor of long-term cardiac outcomes.

Methods and analysis: ENHEARTEN is a multicentre, prospective observational study in a convenience sample of adults (aged >18 years) with their first MI. A total of 450 patients will be recruited over 2 years across two metropolitan health services and one rural/regional health service in Victoria, Australia. The primary outcome of this study will be all-cause, unplanned hospital admissions within 6 months of index admission. Secondary outcomes include cardiac-related hospital admissions up to 24 months post-MI, emergency department presentations, health-related quality of life, mortality, cardiac rehabilitation attendance and healthcare costs. Health literacy will be observed as a predictor variable and will be determined using the 12-item version of the European Health Literacy Survey (HLS-Q12).

Ethics and dissemination: Ethics approval for this study has been received from the relevant human research ethics committee (HREC) at each of the participating health services (lead site Monash Health HREC; approval number: RES-21-0000-242A) and Services Australia HREC (reference number: RMS1672). Informed written consent will be sought from all participants. Study results will be published in peer-reviewed journals and collated in reports for participating health services and participants.

Trial registration number: ACTRN12621001224819.

Keywords: Coronary heart disease; Myocardial infarction; PUBLIC HEALTH.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Cohort Studies
Health Literacy* / methods
Humans
Multicenter Studies as Topic
Myocardial Infarction*
Observational Studies as Topic
Outcome Assessment, Health Care
Prospective Studies
Quality of Life
Victoria

Associated data

ANZCTR/ACTRN12621001224819